Present of a toxin in the salivary glands of the marine snail Cymatium intermedius that targets nicotinic acetylcholine receptors.

@article{West1998PresentOA,
  title={Present of a toxin in the salivary glands of the marine snail Cymatium intermedius that targets nicotinic acetylcholine receptors.},
  author={Dr David J. West and Elizabeth B. Andrews and Alistair R. McVean and Michael C. Thorndyke and John D. Taylor},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={1998},
  volume={36 1},
  pages={25-9}
}
Presence of a toxin in the salivary glands of the marine snail Cymatium intermedius that targets nicotinic acetylcholine receptors. Toxicon 36, 25-29, 1998.-We present evidence of a neurotoxin from the salivary glands of Cymatium intermedius that displays acetylcholine-like effects on vertebrate (mouse ileum) and invertebrate (molluscan smooth muscle; molluscan heart; leech body wall) tissues. These effects were completely blocked by (+)-tubocurarine (10-100 muM) but not by atropine (up to 200… CONTINUE READING

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