Presence of tumor-infiltrating lymphocytes is an independent prognostic factor in type I and II endometrial cancer.

@article{Jong2009PresenceOT,
  title={Presence of tumor-infiltrating lymphocytes is an independent prognostic factor in type I and II endometrial cancer.},
  author={Renske A de Jong and Ninke Leffers and Hendrika M. Boezen and Klaske A. ten Hoor and Ate G J Van Der Zee and Harry Hollema and Hans W Nijman},
  journal={Gynecologic oncology},
  year={2009},
  volume={114 1},
  pages={
          105-10
        }
}
OBJECTIVE Presence of tumor-infiltrating lymphocytes (TIL) is of prognostic importance in a variety of malignancies. This study aims to determine the prognostic value of CD8(+) cytotoxic T-lymphocytes (CTL), FoxP3(+) regulatory T-lymphocytes (Treg) and CD45R0(+) memory T-lymphocytes in endometrial cancer. METHODS The number of tumor-infiltrating CD8(+), FoxP3(+), and CD45R0(+) T-lymphocytes was determined by immunohistochemistry on tissue microarrays containing tumor material from 368 FIGO… CONTINUE READING
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