Presence of spinal B7.2 (CD86) but not B7.1 (CD80) co-stimulatory molecules following peripheral nerve injury: role of nondestructive immunity in neuropathic pain.

@article{Rutkowski2004PresenceOS,
  title={Presence of spinal B7.2 (CD86) but not B7.1 (CD80) co-stimulatory molecules following peripheral nerve injury: role of nondestructive immunity in neuropathic pain.},
  author={Maria D. Rutkowski and Fr{\'e}d{\'e}ric Lambert and Vasudeva Raghavendra and Joyce A Deleo},
  journal={Journal of neuroimmunology},
  year={2004},
  volume={146 1-2},
  pages={94-8}
}
Previous work in our laboratory demonstrated spinal neuroimmune activation and leukocyte trafficking into the central nervous system (CNS) parenchyma in a rat model of neuropathic pain. Recent studies suggest that co-stimulatory molecules B7.1 (CD80) and B7.2 (CD86) play a differential role in the effect of beneficial versus deleterious CNS autoimmune… CONTINUE READING