Presence of nerve growth factor and TrkA expression in the SVZ of EAE rats: evidence for a possible functional significance.

@article{Triaca2005PresenceON,
  title={Presence of nerve growth factor and TrkA expression in the SVZ of EAE rats: evidence for a possible functional significance.},
  author={Viviana Triaca and Paola Tirassa and Luigi Aloe},
  journal={Experimental neurology},
  year={2005},
  volume={191 1},
  pages={53-64}
}
Nerve growth factor (NGF) is a well-characterized neurotrophic factor that plays a crucial role during development in the growth, differentiation, and maintenance of brain neurons as well as in the reparative response of the adult brain to neuronal damage. Recent studies have shown that acute axonal loss occurs in multiple sclerosis (MS) and its animal model, experimental allergic encephalomyelitis (EAE), and that NGF suppresses clinical symptoms of EAE in nonhuman primates. Aim of the present… CONTINUE READING

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