Presence of in vivo-activated T-cells expressing HLA-DR molecules and IL-2 receptors in peripheral blood of patients with nasopharyngeal carcinoma.

@article{Lakhdar1987PresenceOI,
  title={Presence of in vivo-activated T-cells expressing HLA-DR molecules and IL-2 receptors in peripheral blood of patients with nasopharyngeal carcinoma.},
  author={Mahjoub Lakhdar and Radhouane Ellouz and H. Gargouri Kammoun and S Ben H'Tira and N Khedhiri and Radhia Kastally and Wolf H Fridman},
  journal={International journal of cancer},
  year={1987},
  volume={39 6},
  pages={
          663-9
        }
}
Epstein-Barr Virus (EBV) is associated with two malignant diseases, African Burkitt's Lymphoma (BL) and Undifferentiated Nasopharyngeal Carcinoma (UNPC). North Africa is a geographical area with a high incidence of NPC. Our purpose in this study was to explore cell-mediated immunity of peripheral blood lymphocytes (PBL) from patients with UNPC and DNPC. We found an elevated percentage of OKT8 cells and of large granular lymphocytes (LGL) (30-35% HNK-I-positive cells) compared to PBL from… CONTINUE READING
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