Presence of functional oxytocin receptors in cultured human myoblasts.

  title={Presence of functional oxytocin receptors in cultured human myoblasts.},
  author={Christophe Breton and Christine Haenggeli and Claude Barberis and Freddy Heitz and Charles Roland Bader and Laurent Bernheim and Eliane Tribollet},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={87 3},
In the present report, we provide for the first time evidence that functional oxytocin receptors (OTRs) are present in human myoblasts obtained from clonal cultures of postnatal satellite cells. First, binding studies performed with a non selective vasopressin (AVP) and oxytocin (OT) radioligand indicated the presence of a single class of binding sites. Second, OTR mRNA was detected by RT-PCR analysis whereas transcripts for AVP V(1a), V(1b) or V(2) receptors (V(1a)R, V(1b)R and V(2)R… CONTINUE READING