Presence of foam cells containing oxidised low density lipoprotein in the synovial membrane from patients with rheumatoid arthritis.

@article{Winyard1993PresenceOF,
  title={Presence of foam cells containing oxidised low density lipoprotein in the synovial membrane from patients with rheumatoid arthritis.},
  author={Paul G. Winyard and Franz Tatzber and Hermann Esterbauer and Monika Kus and David R. Blake and Christopher J. Morris},
  journal={Annals of the rheumatic diseases},
  year={1993},
  volume={52 9},
  pages={677-80}
}
OBJECTIVE Increased concentrations of lipid peroxidation products have been described in the serum and synovial fluid from patients with rheumatoid arthritis. A large proportion of the unsaturated lipids in human extracellular fluids is a component of low density lipoprotein (LDL). The oxidative modification of LDL, and its subsequent uptake by macrophages, has been implicated in the pathogenesis of atherosclerosis, but not of rheumatoid arthritis. This study aimed to assess whether oxidatively… CONTINUE READING

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