Presence of filterable and nonfilterable mRNA in the plasma of cancer patients and healthy individuals.

@article{Ng2002PresenceOF,
  title={Presence of filterable and nonfilterable mRNA in the plasma of cancer patients and healthy individuals.},
  author={Enders K. O. Ng and Nancy B Y Tsui and Nicole Y-L Lam and Rossa W. K. Chiu and Simon Chun Ho Yu and S. C. Cesar Wong and Elena Siu Fong Lo and Timothy Hudson Rainer and Philip James Johnson and Yuk Ming Dennis Lo},
  journal={Clinical chemistry},
  year={2002},
  volume={48 8},
  pages={1212-7}
}
BACKGROUND As RNA is labile, we investigated whether circulating RNA in human plasma may be present in a particle-associated form. METHODS Blood was collected from 27 healthy individuals and 16 hepatocellular carcinoma (HCC) patients. The plasma from each individual was processed by two means: filtration through filters with different pore sizes (from 5… CONTINUE READING