Presence of fetal DNA in maternal plasma and serum.

  title={Presence of fetal DNA in maternal plasma and serum.},
  author={Y. M. Lo and N Corbetta and Paul Chamberlain and Varun Rai and Ian I L Sargent and Christopher W. G. Redman and J Stephen Wainscoat},
  volume={350 9076},
BACKGROUND The potential use of plasma and serum for molecular diagnosis has generated interest. Tumour DNA has been found in 'the plasma and serum of cancer patients, and molecular analysis has been done on this material. We investigated the equivalent condition in pregnancy-that is, whether fetal DNA is present in maternal plasma and serum. METHODS We used a rapid-boiling method to extract DNA from plasma and serum. DNA from plasma, serum, and nucleated blood cells from 43 pregnant women… CONTINUE READING
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ESF,Watson N, et al.Two-way cell traffic between mother and fetus biologic and clinical implications

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  • Blood
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