Presence of circulating antibodies against cellular protein p53 in a notable proportion of children with B-cell lymphoma.

@article{Fromentel1987PresenceOC,
  title={Presence of circulating antibodies against cellular protein p53 in a notable proportion of children with B-cell lymphoma.},
  author={Claude Caron de Fromentel and F. May-Levin and H. Mouriesse and Jean Lemerle and Krish Chandrasekaran and Pierre May},
  journal={International journal of cancer},
  year={1987},
  volume={39 2},
  pages={185-9}
}
Serum samples taken from children bearing a wide variety of tumors were screened for the presence of circulating antibodies against the cellular tumor antigen p53. There was a significant correlation (p less than 0.001, n = 119) between the presence of such antibodies and the occurrence of cancer; 12% of the sera tested were positive. These sera were derived from children with a wide range of tumor types. In particular, 21% of the sera obtained from children suffering from a B-cell lymphoma… CONTINUE READING

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