Presence of angiotensin converting enzyme in the adventitia of large blood vessels

@article{Rogerson1992PresenceOA,
  title={Presence of angiotensin converting enzyme in the adventitia of large blood vessels},
  author={Fraser M. Rogerson and Siew Yeen Chai and Ingrid Schlawe and William K. Murray and Philip D. Marleyt and Frederick A. O. Mendelsohn},
  journal={Journal of Hypertension},
  year={1992},
  volume={10},
  pages={615–620}
}
Background: Angiotensin converting enzyme (ACE) is present in the endothelial cells of all vascular beds. There are, however, many reports of converting enzyme activity in blood vessels not associated with the endothelium. Methods: ACE was localized in large blood vessels of a number of mammals by in vitro autoradiography using the radioligand 125I-351A. To characterize this binding further, immunohistochemistry was performed on rabbit aorta using polyclonal antisera raised to two different… 

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