Presence of a group II intron in a multiresistant Serratia marcescens strain that harbors three integrons and a novel gene fusion.

@article{Centrn2002PresenceOA,
  title={Presence of a group II intron in a multiresistant Serratia marcescens strain that harbors three integrons and a novel gene fusion.},
  author={Daniela Centr{\'o}n and Paul H. Roy},
  journal={Antimicrobial agents and chemotherapy},
  year={2002},
  volume={46 5},
  pages={1402-9}
}
We analyzed the role of integrons in the dissemination of antibiotic resistance in a recent multiresistant clinical isolate, Serratia marcescens SCH88050909 (SCH909). This isolate harbors three integrons, all on a 60-kb conjugative plasmid. By PCR, hybridization, and sequencing analyses, we found that integron 1 has the dfrA1 and ant(3")-Ia cassettes. The first cassette in integron 2 contains the ant(2")-Ia gene, separated from its attC site (59-base element) by a 1,971-bp insert containing a… CONTINUE READING