Presence of a characteristic D-D-E motif in IS1 transposase.

@article{Ohta2002PresenceOA,
  title={Presence of a characteristic D-D-E motif in IS1 transposase.},
  author={Shinya Ohta and Ken Tsuchida and Sunju Choi and Yasuhiko Sekine and Yasuyuki Shiga and Eiichi Ohtsubo},
  journal={Journal of bacteriology},
  year={2002},
  volume={184 22},
  pages={
          6146-54
        }
}
Transposases encoded by various transposable DNA elements and retroviral integrases belong to a family of proteins with three conserved acidic amino acids, D, D, and E, constituting the D-D-E motif that represents the active center of the proteins. IS1, one of the smallest transposable elements in bacteria, encodes a transposase which has been thought not to belong to the family of proteins with the D-D-E motif. In this study, we found several IS1 family elements that were widely distributed… CONTINUE READING

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