Presence of Epstein-Barr virus in extranodal T-cell lymphomas: differences in relation to site.

@article{Bruin1994PresenceOE,
  title={Presence of Epstein-Barr virus in extranodal T-cell lymphomas: differences in relation to site.},
  author={P C de Bruin and Mehdi Jiwa and J. J. Oudejans and Paul D. L. P. M. van der Valk and P van Heerde and Jean Christophe Sabourin and G Csanaky and Philippe Gaulard and Arnold L Noorduyn and Rein Willemze},
  journal={Blood},
  year={1994},
  volume={83 6},
  pages={1612-8}
}
T-cell lymphomas with similar morphology but with different sites of origin have a different clinical behavior. The theoretical explanation for this finding originates from the hypothesis that non-Hodgkin's lymphomas (NHLs) are neoplastic equivalents of immunological reactions involving tissue-restricted lymphocytes. This hypothesis also implies that T-NHLs originating from different sites differ in their genesis, and thus may differ in oncogen expression, expression of adhesion molecules, or… CONTINUE READING
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