Presence of Anti-Microbial Antibodies in Liver Cirrhosis – A Tell-Tale Sign of Compromised Immunity?

@inproceedings{Papp2010PresenceOA,
  title={Presence of Anti-Microbial Antibodies in Liver Cirrhosis – A Tell-Tale Sign of Compromised Immunity?},
  author={M{\'a}ria Papp and Gary L Norman and Zsuzsanna Vitalis and Istvan Tornai and Istv{\'a}n Altorjay and Ildiko Foldi and Miklos D. F. Udvardy and Zakera Shums and Tam{\'a}s Dinya and Peter Orosz and B{\'e}la Lombay and Gabriella Par and Alajos P{\'a}r and Gabor Istvan Veres and T{\'i}mea Cs{\'a}k and J{\'a}nos Osztovits and Ferenc A. de Szalay and Peter L Lakatos},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Bacterial translocation plays important role in the complications of liver cirrhosis. Antibody formation against various microbial antigens is common in Crohn's disease and considered to be caused by sustained exposure to gut microflora constituents. We hypothesized that anti-microbial antibodies are present in patients with liver cirrhosis and may be associated with the development of bacterial infections. METHODOLOGY/PRINCIPAL FINDINGS Sera of 676 patients with various chronic… CONTINUE READING

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