Presence and mRNA expression of T3 receptors in differentiating rat brown adipocytes.


Nuclear T3 binding and T3 receptors (TR) expression were studied in brown adipocytes differentiated in culture from precursor cells. High affinity T3 receptors were found. During adipocyte differentiation maximal binding capacity (MBC) was doubled (up to 763 fmol T3/mg DNA), and an apparent decrease in receptor affinity was also observed (due to a decrease… (More)


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