Presence and absence of follicle-stimulating hormone receptor mutations provide some insights into spontaneous ovarian hyperstimulation syndrome physiopathology.

@article{Leener2006PresenceAA,
  title={Presence and absence of follicle-stimulating hormone receptor mutations provide some insights into spontaneous ovarian hyperstimulation syndrome physiopathology.},
  author={Anne De Leener and Lucia Montanelli and Joost J J Van Durme and Heedong Chae and Guillaume Smits and G. Vassart and Sabine Costagliola},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2006},
  volume={91 2},
  pages={555-62}
}
CONTEXT Ovarian hyperstimulation syndrome (OHSS) is a potentially life-threatening complication of ovarian stimulation treatments. Moreover, four mutations of the FSH receptor (FSHr) were recently described in patients presenting with spontaneous OHSS (sOHSS) of the first trimester of pregnancy with normal levels of human chorionic gonadotropin (hCG). OBJECTIVE The objective of this study was to look for novel FSHr mutations in patients with sOHSS associated with different levels of hCG and… CONTINUE READING

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DESIGN , INTERVENTION , AND PATIENTS : After blood sampling , we sequenced the FSHr from genomic leukocytes DNA from eight patients with sOHSS of the first or second trimester of pregnancy with normal or high hCG levels or with high TSH levels associated with severe hypothyroidism . SETTING .
DESIGN , INTERVENTION , AND PATIENTS : After blood sampling , we sequenced the FSHr from genomic leukocytes DNA from eight patients with sOHSS of the first or second trimester of pregnancy with normal or high hCG levels or with high TSH levels associated with severe hypothyroidism . SETTING .
Ovarian hyperstimulation syndrome ( OHSS ) is a potentially life - threatening complication of ovarian stimulation treatments .
Ovarian hyperstimulation syndrome ( OHSS ) is a potentially life - threatening complication of ovarian stimulation treatments .
Ovarian hyperstimulation syndrome ( OHSS ) is a potentially life - threatening complication of ovarian stimulation treatments .
Ovarian hyperstimulation syndrome ( OHSS ) is a potentially life - threatening complication of ovarian stimulation treatments .
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