Prescription opioids. III. Disposition of oxycodone in oral fluid and blood following controlled single-dose administration.

@article{Cone2015PrescriptionOI,
  title={Prescription opioids. III. Disposition of oxycodone in oral fluid and blood following controlled single-dose administration.},
  author={Edward J. Cone and Anne Depriest and Rebecca Heltsley and David L. Black and John M Mitchell and Charles P Lodico and Ron Flegel},
  journal={Journal of analytical toxicology},
  year={2015},
  volume={39 3},
  pages={192-202}
}
Oxycodone (OC) is recommended to be included as an analyte tested in the proposed Substance Abuse and Mental Health Services Administration (SAMHSA's) Mandatory Guidelines for Federal Workplace Drug Testing Programs using Oral Fluid (OF) Specimens. This study demonstrates the time course of OC and metabolites, noroxycodone (NOC), oxymorphone (OM) and noroxymorphone (NOM), in near-simultaneous paired OF and whole blood (BL) specimens by liquid chromatography-tandem mass spectrometry (LC-MS-MS… CONTINUE READING