Prescription n-3 Fatty Acids, But Not Eicosapentaenoic Acid Alone, Improve Reference Memory-Related Learning Ability by Increasing Brain-Derived Neurotrophic Factor Levels in SHR.Cg-Leprcp/NDmcr rats, A Metabolic Syndrome Model

@article{Hashimoto2013PrescriptionNF,
  title={Prescription n-3 Fatty Acids, But Not Eicosapentaenoic Acid Alone, Improve Reference Memory-Related Learning Ability by Increasing Brain-Derived Neurotrophic Factor Levels in SHR.Cg-Leprcp/NDmcr rats, A Metabolic Syndrome Model},
  author={M. Hashimoto and Takayuki Inoue and M. Katakura and Y. Tanabe and S. Hossain and S. Tsuchikura and O. Shido},
  journal={Neurochemical Research},
  year={2013},
  volume={38},
  pages={2124 - 2135}
}
Metabolic syndrome is implicated in the decline of cognitive ability. We investigated whether the prescription n-3 fatty acid administration improves cognitive learning ability in SHR.Cg-Leprcp/NDmcr (SHR-cp) rats, a metabolic syndrome model, in comparison with administration of eicosapentaenoic acid (EPA, C20:5, n-3) alone. Administration of TAK-085 [highly purified and concentrated n-3 fatty acid formulation containing EPA ethyl ester and docosahexaenoic acid (DHA, C22:6, n-3) ethyl ester] at… Expand
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