Prescription Opioids. IV: Disposition of Hydrocodone in Oral Fluid and Blood Following Single-Dose Administration.

@article{Cone2015PrescriptionOI,
  title={Prescription Opioids. IV: Disposition of Hydrocodone in Oral Fluid and Blood Following Single-Dose Administration.},
  author={Edward J. Cone and Anne Depriest and Rebecca Heltsley and David L. Black and John M Mitchell and Charles P Lodico and Ron Flegel},
  journal={Journal of analytical toxicology},
  year={2015},
  volume={39 7},
  pages={510-8}
}
The Substance Abuse and Mental Health Services Administration (SAMHSA) is currently evaluating hydrocodone (HC) for inclusion in the Mandatory Guidelines for Federal Workplace Drug Testing Programs. This study evaluated the time course of HC, norhydrocodone (NHC), dihydrocodeine (DHC) and hydromorphone (HM) in paired oral fluid and whole blood specimens by liquid chromatography-tandem mass spectrometry (limit of quantitation = 1 ng/mL of oral fluid, 5 ng/mL of blood) over a 52-h period. A… CONTINUE READING
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