Prepulse inhibition predicts working memory performance whilst startle habituation predicts spatial reference memory retention in C57BL/6 mice

@article{Singer2013PrepulseIP,
  title={Prepulse inhibition predicts working memory performance whilst startle habituation predicts spatial reference memory retention in C57BL/6 mice},
  author={Philipp Singer and Jonas Hauser and Luis H. Llano Lopez and Daria Peleg-Raibstein and Benjamin L. Yee},
  journal={Behavioural Brain Research},
  year={2013},
  volume={242},
  pages={166-177}
}
Prepulse inhibition (PPI) of the acoustic startle reflex refers to the attenuation of the startle response to an intense pulse stimulus when it is shortly preceded by a weak non-startling prepulse stimulus. It is a well-established high-throughput translational measure of pre-attentive sensory gating, and its impairment is detected in several neuropsychiatric diseases including schizophrenia. It has been hypothesized that PPI might be associated with, or predictive of, cognitive deficiency in… CONTINUE READING
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Individual difference in prepulse inhibition does not predict spatial learning and memory performance in C57BL/6 mice

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  • 2015
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