Prepulse Inhibition of Acoustic Startle Reflex as a Function of the Frequency Difference between Prepulse and Background Sounds in Mice

@article{Basavaraj2012PrepulseIO,
  title={Prepulse Inhibition of Acoustic Startle Reflex as a Function of the Frequency Difference between Prepulse and Background Sounds in Mice},
  author={S. Basavaraj and J. Yan},
  journal={PLoS ONE},
  year={2012},
  volume={7}
}
  • S. Basavaraj, J. Yan
  • Published 2012
  • Medicine
  • PLoS ONE
  • Background Prepulse inhibition (PPI) depicts the effects of a weak sound preceding strong acoustic stimulus on acoustic startle response (ASR). Previous studies suggest that PPI is influenced by physical parameters of prepulse sound such as intensity and preceding time. The present study characterizes the impact of prepulse tone frequency on PPI. Methods Seven female C57BL mice were used in the present study. ASR was induced by a 100 dB SPL white noise burst. After assessing the effect of… CONTINUE READING
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