Preprotachykinin A mRNA is colocalized with tyrosine hydroxylase-immunoreactivity in bulbospinal neurons

@article{Li2005PreprotachykininAM,
  title={Preprotachykinin A mRNA is colocalized with tyrosine hydroxylase-immunoreactivity in bulbospinal neurons},
  author={Qiushuang Li and Ann K Goodchild and Maryam Seyedabadi and Paul M. Pilowsky},
  journal={Neuroscience},
  year={2005},
  volume={136},
  pages={205-216}
}
Previous studies have generated controversy about the extent of co-localization between substance P- and catecholamine-containing neurons that project to the spinal cord. In earlier studies, estimates using immunofluorescence after colchicine have ranged from almost all, to almost none. We sought to resolve this issue by combining in situ hybridization and immunofluorescence. Catecholamine (A1 to A7, C1 to C3; tyrosine hydroxylase immunoreactive) neurons in the rat brainstem were examined to… CONTINUE READING
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