Preproenkephalin mRNA is expressed by C1 and non-C1 barosensitive bulbospinal neurons in the rostral ventrolateral medulla of the rat.

@article{Stornetta2001PreproenkephalinMI,
  title={Preproenkephalin mRNA is expressed by C1 and non-C1 barosensitive bulbospinal neurons in the rostral ventrolateral medulla of the rat.},
  author={Ruth L Stornetta and Ann M Schreihofer and Nicole M Pelaez and Charles P. Sevigny and Patrice G Guyenet},
  journal={The Journal of comparative neurology},
  year={2001},
  volume={435 1},
  pages={111-26}
}
The autonomic regions of the thoracolumbar spinal cord receive a dense enkephalinergic (ENK) innervation from supraspinal sources, including the rostral ventrolateral medulla (RVLM). In the present study, we sought to determine whether the barosensitive bulbospinal (BSBS) neurons of the RVLM express preproenkephalin (PPE) mRNA. After injection of Fluoro-Gold (FG) into the upper thoracic spinal cord, neurons with PPE mRNA (PPE(+) neurons) were retrogradely labeled throughout the ventrolateral… CONTINUE READING

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