Preproenkephalin (Penk) is Expressed in Differentiated Osteoblasts, and its Deletion in Hyp Mice Partially Rescues Their Bone Mineralization Defect

Abstract

Although our understanding of the molecular mechanisms controlling osteoblast differentiation and function is steadily increasing, there are still many open questions, especially regarding the regulation of bone matrix mineralization. For instance, while there is hallmark evidence for the importance of the endopeptidase Phex, whose inactivation in Hyp mice… (More)
DOI: 10.1007/s00223-010-9344-5

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