Prepore for a breakthrough

  title={Prepore for a breakthrough},
  author={Hagan Bayley and Lakmal Jayasinghe and Mark Wallace},
  journal={Nature Structural &Molecular Biology},
Proteinaceous pore-forming toxins (PFTs) are secreted by many species of infectious bacteria. They may simply permeabilize or lyse mammalian cell targets causing nonspecific damage beneficial to the aggressor, such as the release of nutrients. Alternatively, they may behave more shrewdly and provide a pathway for the translocation of toxin subunits with… CONTINUE READING