Preparing for preventive clinical trials: the Predict-HD study.

@article{Paulsen2006PreparingFP,
  title={Preparing for preventive clinical trials: the Predict-HD study.},
  author={Jane S. Paulsen and Michael R. Hayden and Julie C. Stout and Douglas R. Langbehn and Elizabeth H. Aylward and Christopher A. Ross and Mark Guttman and Martha A. Nance and Karl K Kieburtz and David Oakes and Ira Shoulson and Elise Kayson and Shannon Johnson and Elizabeth Penziner},
  journal={Archives of neurology},
  year={2006},
  volume={63 6},
  pages={
          883-90
        }
}
BACKGROUND The optimal design and outcome measures for preventive clinical trials in neurodegenerative diseases are unknown. OBJECTIVE To examine measures that may be associated with disease in the largest cohort ever recruited of prediagnosed individuals carrying the gene expansion for Huntington disease (HD). DESIGN The Predict-HD study is a multicenter observational research study in progress at 17 sites in the United States, 4 in Canada, and 3 in Australia. SETTING Genetics and HD… CONTINUE READING
BETA

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 136 CITATIONS, ESTIMATED 57% COVERAGE

243 Citations

0102030'07'10'13'16'19
Citations per Year
Semantic Scholar estimates that this publication has 243 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
SHOWING 1-10 OF 33 REFERENCES

A new model for prediction of the age of onset and penetrance for Huntington's disease based on

  • DR Langbehn, R Brinkman, D Faulush, JS Paulsen, MR. Hayden
  • CAG length. Clin Genet
  • 2004
2 Excerpts

Similar Papers

Loading similar papers…