Preparative merits of the mixed anhydride (MA) method in the excess use of DDZ-amino acids in the peptide synthesis of biologically active new antamanide analogues.

@article{Birr1979PreparativeMO,
  title={Preparative merits of the mixed anhydride (MA) method in the excess use of DDZ-amino acids in the peptide synthesis of biologically active new antamanide analogues.},
  author={Cynthia Birr and Michael Nassal and Ruediger Pipkorn},
  journal={International journal of peptide and protein research},
  year={1979},
  volume={13 3},
  pages={287-95}
}
The mixed anhydride (MA) method of peptide synthesis is further simplified by the repetitive excess use of Ddz-amino acids. In six comparative preparations of decapeptides this is demonstrated by the ease and speed of the synthetic manipulations, the efficiency of the monitoring of the reactions and purifications, and by the complete recycling of excess… CONTINUE READING