Preparation of the modular multi-domain protein RPA for study by NMR spectroscopy.

@article{Brosey2012PreparationOT,
  title={Preparation of the modular multi-domain protein RPA for study by NMR spectroscopy.},
  author={Chris A. Brosey and Marie-Eve Chagot and Walter J Chazin},
  journal={Methods in molecular biology},
  year={2012},
  volume={831},
  pages={181-95}
}
The integrity and propagation of the genome depend upon the fidelity of DNA processing events, such as replication, damage recognition, and repair. Requisite to the numerous biochemical tasks required for DNA processing is the generation and manipulation of single-stranded DNA (ssDNA). As the primary eukaryotic ssDNA-binding protein, Replication Protein A… CONTINUE READING