Preparation of sub-100-nm beta-lactoglobulin (BLG) nanoparticles.

  title={Preparation of sub-100-nm beta-lactoglobulin (BLG) nanoparticles.},
  author={Sanghoon Ko and Sundaram Gunasekaran},
  journal={Journal of microencapsulation},
  volume={23 8},
Sub-100-nm nanoparticles were prepared from beta-lactoglobulin (BLG) with a narrow size distribution by a desolvation method using glutaraldehyde for cross-linking. With pre-heating of the BLG solution to 60 degrees C and subsequent pH readjustment to 9.0, nanoparticles of 59 +/- 5 nm were obtained with improved uniformity. Bovine serum albumin (BSA) nanoparticles, prepared under similar conditions for comparison, were larger and less uniform. The half-width of 80% particle distribution was… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 37 references

Optimization of the preparation process for human serum albumin (HSA) nanoparticles.

International journal of pharmaceutics • 2003
View 5 Excerpts
Highly Influenced

Preparation of small - sized particles from vicilin ( vegetal protein from Pisum sativum L ) by coacervation

A Gopferich
European Journal of Pharmaceutics and Biopharmaceutics • 1996
View 1 Excerpt
Highly Influenced

Proteins in whey: chemical, physical, and functional properties.

Advances in food and nutrition research • 1989
View 3 Excerpts
Highly Influenced

Human serum albumin-polyethylenimine nanoparticles for gene delivery.

Journal of controlled release : official journal of the Controlled Release Society • 2003
View 1 Excerpt

Advanced Drug Delivery Reviews 34:171–189

peptides, peptidomimetics
Arnedo A, Espuelas S, Irache JM • 2002