Preparation of radioactive iodinated cholylhistamine for use in the radioimmunoassay of cholic acid.

@article{Weinberg1977PreparationOR,
  title={Preparation of radioactive iodinated cholylhistamine for use in the radioimmunoassay of cholic acid.},
  author={P B Weinberg and Joseph M. Kinkade and Delwood C. Collins},
  journal={Steroids},
  year={1977},
  volume={30 5},
  pages={637-45}
}
A major handicap in the development of simple and accurate radioimmunoassay procedures for bile acids has been the lack of a radioactive standard of high specific activity. To provide such a compound, we first synthesized cholylhistamine using the carbodiimide reaction. The hypothesized structure was confirmed by elemental analysis, thin-layer… CONTINUE READING