Preparation of murine monoclonal antibodies against the yeast phase of the dimorphic fungus Sporothrix schenckii.

@article{Hamilton1990PreparationOM,
  title={Preparation of murine monoclonal antibodies against the yeast phase of the dimorphic fungus Sporothrix schenckii.},
  author={Andrew John Hamilton and Takashi Harada and Mark Bartholomew and Jose I. Figueroa and Lynda Fenelon and Rod J. Hay},
  journal={Transactions of the Royal Society of Tropical Medicine and Hygiene},
  year={1990},
  volume={84 5},
  pages={734-7}
}
Three murine monoclonal antibodies (Mabs) were raised against a cytoplasmic antigen of the yeast phase of the pathogenic fungus Sporothrix schenckii using a modification of standard hybridoma technology incorporating the immunosuppressive drug cyclophosphamide. When tested for species-specificity within the pathogenic dimorphic fungi one of these Mabs (S5… CONTINUE READING