Preparation of monoclonal antibodies to the thrombin/hirudin complex.

Abstract

Monoclonal antibodies (mAbs) binding to the thrombin/hirudin (T.H) complex were prepared by either immunizing mice with hirudin and by screening for the mAbs cross-reacting with the T.H complex (group I), or by immunizing the animals directly with the T.H complex (group II). Epitope mapping of the mAbs of group I indicated that all the mAbs were binding to… (More)

Topics

Cite this paper

@article{Schlaeppi1991PreparationOM, title={Preparation of monoclonal antibodies to the thrombin/hirudin complex.}, author={Jean Marc Schlaeppi}, journal={Thrombosis research}, year={1991}, volume={62 5}, pages={459-70} }