Preparation of liposomal brucine and its pharmaceutical/pharmacodynamic characterization

Xiang-qi Qin, Yuan Yuan, Chang-Sheng Liu, Qiu-yun Wang, Xi Shen, Bai-can Yang
Published 2007 in Acta Pharmacologica Sinica

Abstract

AbstractAim:To prepare a novel transdermal preparation of liposomal brucine (LB) and investigate its pharmaceutical/pharmacodynamic characterization.Methods:LB was prepared by a modified ethanol-dripping method. Its drug encapsulation efficiency (EE), particle size, in vitro release, and skin permeation were studied. Furthermore, a safety evaluation and… (More)

DOI: 10.1111/j.1745-7254.2007.00654.x

Topics

11 Figures and Tables

Cited By

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Preparation of liposomal brucine and its pharmaceutical/pharmacodynamic characterization

Abstract

Topics

11 Figures and Tables

Cited By

A Novel Brucine Gel Transdermal Delivery System Designed for Anti-Inflammatory and Analgesic Activities

Effect of Ultrasound-Enhanced Transdermal Drug Delivery Efficiency of Nanoparticles and Brucine

Pharmacological evaluation of total alkaloids from nux vomica: effect of reducing strychnine contents.

Anti-inflammatory and antinociceptive effects of Chinese medicine SQ gout capsules and its modulation of pro-inflammatory cytokines focusing on gout arthritis.

Preparation, characterization and tissue distribution of brucine stealth liposomes with different lipid composition.

Analgesic and anti-inflammatory activity and pharmacokinetics of alkaloids from seeds of Strychnos nux-vomica after transdermal administration: effect of changes in alkaloid composition.

Improved pharmacokinetics and reduced toxicity of brucine after encapsulation into stealth liposomes: role of phosphatidylcholine

Study of pharmacokinetics and tissue distribution of liposomal brucine for dermal administration

References

Comparative efficacy of liposome-entrapped amiloride and free amiloride in animal models of seizures and serum potassium in mice

Safety studies on epigallocatechin gallate (EGCG) preparations. Part 2: dermal, acute and short-term toxicity studies.

Safety and toxicological evaluation of a novel niacin-bound chromium (III) complex.

Study and development of encapsulated form of 4, 5, 8trimethylpsoralen for topical drug delivery

Analgesic and anti-inflammatory properties of brucine and brucine N-oxide extracted from seeds of Strychnos nux-vomica.

Particle size of liposomes influences dermal delivery of substances into skin.

Study on optimize the preparation and formulation of nimodipine-containing nanoliposome

Preparation and pharmacodynamic evaluation of liposomes of indomethacin.

Liposome encapsulated vitamin A compounds exhibit greater stability and diminished toxicity.

Liposomes as carriers for topical and transdermal delivery.

Slides referencing similar topics

Preparation of liposomal brucine and its pharmaceutical/pharmacodynamic characterization

Abstract

Topics

11 Figures and Tables

Cited By

A Novel Brucine Gel Transdermal Delivery System Designed for Anti-Inflammatory and Analgesic Activities

Effect of Ultrasound-Enhanced Transdermal Drug Delivery Efficiency of Nanoparticles and Brucine

Pharmacological evaluation of total alkaloids from nux vomica: effect of reducing strychnine contents.

Anti-inflammatory and antinociceptive effects of Chinese medicine SQ gout capsules and its modulation of pro-inflammatory cytokines focusing on gout arthritis.

Preparation, characterization and tissue distribution of brucine stealth liposomes with different lipid composition.

Analgesic and anti-inflammatory activity and pharmacokinetics of alkaloids from seeds of Strychnos nux-vomica after transdermal administration: effect of changes in alkaloid composition.

Improved pharmacokinetics and reduced toxicity of brucine after encapsulation into stealth liposomes: role of phosphatidylcholine

Study of pharmacokinetics and tissue distribution of liposomal brucine for dermal administration

References

Comparative efficacy of liposome-entrapped amiloride and free amiloride in animal models of seizures and serum potassium in mice

Safety studies on epigallocatechin gallate (EGCG) preparations. Part 2: dermal, acute and short-term toxicity studies.

Safety and toxicological evaluation of a novel niacin-bound chromium (III) complex.

Study and development of encapsulated form of 4, 5, 8trimethylpsoralen for topical drug delivery

Analgesic and anti-inflammatory properties of brucine and brucine N-oxide extracted from seeds of Strychnos nux-vomica.

Particle size of liposomes influences dermal delivery of substances into skin.

Study on optimize the preparation and formulation of nimodipine-containing nanoliposome

Preparation and pharmacodynamic evaluation of liposomes of indomethacin.

Liposome encapsulated vitamin A compounds exhibit greater stability and diminished toxicity.

Liposomes as carriers for topical and transdermal delivery.

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Slides referencing similar topics