Preparation of inhalable salbutamol sulphate using reactive high gravity controlled precipitation.

Abstract

Reactive high gravity controlled precipitation (HGCP) was carried out to produce salbutamol sulphate (SS) particles suitable for inhalation. Aqueous solutions of free salbutamol base and sulphuric acid were mixed intensely inside a HGCP reactor to form the particles. Spray drying was employed to obtain dry powders. Physical properties of the powders were… (More)

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Cite this paper

@article{Hu2008PreparationOI, title={Preparation of inhalable salbutamol sulphate using reactive high gravity controlled precipitation.}, author={Tingting Hu and Herbert Chiou and H. Chan and Jian-Feng Chen and Jimmy Yun}, journal={Journal of pharmaceutical sciences}, year={2008}, volume={97 2}, pages={944-9} }