Preparation of curcumin-loaded liposomes and evaluation of their skin permeation and pharmacodynamics.

  title={Preparation of curcumin-loaded liposomes and evaluation of their skin permeation and pharmacodynamics.},
  author={Yan Chen and Qingqing Wu and Zhenghai Zhang and Ling Yuan and Xuan Ming Liu and Lei Zhou},
  volume={17 5},
This study aimed to investigate the in vitro skin permeation and in vivo antineoplastic effect of curcumin by using liposomes as the transdermal drug-delivery system. Soybean phospholipids (SPC), egg yolk phospholipids (EPC), and hydrogenated soybean phospholipids (HSPC) were selected for the preparation of different kinds of phospholipids composed of curcumin-loaded liposomes: C-SPC-L (curcumin-loaded SPC liposomes), C-EPC-L (curcumin-loaded EPC liposomes), and C-HSPC-L (curcumin-loaded HSPC… CONTINUE READING


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