Preparation of chitosan-gelatin hybrid scaffolds with well-organized microstructures for hepatic tissue engineering.

@article{Jiankang2009PreparationOC,
  title={Preparation of chitosan-gelatin hybrid scaffolds with well-organized microstructures for hepatic tissue engineering.},
  author={He Jian-kang and L. Dichen and Liu Yaxiong and Yao Bo and Zhan Hanxiang and L. Qin and Lu Bingheng and L. Yi},
  journal={Acta biomaterialia},
  year={2009},
  volume={5 1},
  pages={
          453-61
        }
}
The structural organization of natural liver is instrumental in the multifunctionality of hepatocytes, and mimicking these specific architectures in tissue-engineered scaffold plays an important role in the engineering of an implantable liver equivalent in vitro. To achieve this goal, we have developed a novel fabrication process to create chitosan-gelatin hybrid scaffolds with well-organized architectures and highly porous structures by combining rapid prototyping, microreplication and freeze… Expand
Development of a 3D porous chitosan/gelatin liver scaffold for a bioartificial liver device.
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