Preparation of a "chemical vaccine" against tumor progression.

Abstract

A synthetic antigen containing the presumed receptor site for wheat-germ agglutinin (a lectin capable of specifically agglutinating tumor cells) elicits an immune response in mice capable of cross-reacting with receptor sites for wheat-germ agglutinin on tumor-cell surfaces. Mice immunized against the antigen in complete Freund's adjuvant are able to reject… (More)

Topics

9 Figures and Tables