Preparation of CO2 from blood and protein-bound amino acid carboxyl groups for quantification and 13C-isotope measurements.

@article{Read1984PreparationOC,
  title={Preparation of CO2 from blood and protein-bound amino acid carboxyl groups for quantification and 13C-isotope measurements.},
  author={W W Read and Mark A. Read and Michael John Rennie and Robert Griggs and David F. Halliday},
  journal={Biomedical mass spectrometry},
  year={1984},
  volume={11 7},
  pages={348-52}
}
Measurements of protein and amino acid metabolism in man using stable isotopes and selected ion monitoring gas chromatographic/mass spectrometric techniques are limited by the requirement of relatively high levels of labelling for adequate precision (greater than 0.05 at % excess). We describe here a means of extending the scope of such studies by measurement of lower levels of enrichment achieved in gaseous CO2 derived from whole blood or protein-bound amino acids following the administration… CONTINUE READING

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