Preparation of Aryl-Susbstituted 2-Oxyindoles by Superelectrophilic Chemistry.

@article{Naredla2013PreparationOA,
  title={Preparation of Aryl-Susbstituted 2-Oxyindoles by Superelectrophilic Chemistry.},
  author={Rajasekhar Reddy Naredla and Erum K Raja and Douglas A Klumpp},
  journal={Tetrahedron letters},
  year={2013},
  volume={54 25},
  pages={3245-3247}
}
A series of pyridyl-substituted 3-hydroxy-2-oxyindoles have been prepared and reacted with arenes in superacid promoted Friedel-Crafts reactions. The product aryl-substituted 2-oxyindoles are formed in generally good yields. With substituted arenes such as toluene, bromobenzene, or ethyl salicylate, the Friedel-Crafts reactions occur with excellent… CONTINUE READING