Corpus ID: 103615939

Preparation method of 6-chloro-1,3-dimethyluracil

@inproceedings{2012PreparationMO,
  title={Preparation method of 6-chloro-1,3-dimethyluracil},
  author={江成真 and 张恩选 and 宁述光 and 夏松 and 程经纬},
  year={2012}
}
The invention provides a preparation method of 6-chloro-1,3-dimethyluracil, which comprises the following steps: carry out reflux reaction on 1,3-dimethylbarbituric acid and a chlorinating agent in a water-insoluble organic solvent to obtain a reaction mixture; and adding water to quench the reaction to obtain the 6-chloro-1,3-dimethyluracil, wherein the chlorinating agent comprises phosphorus oxychloride. The preparation method provided by the invention reduces the consumption of phosphorus… Expand