Preparation and in vivo evaluation of 90Y-meso-dimercaptosuccinic acid (90Y-DMSA) for possible therapeutic use: comparison with 99mTc-DMSA.

Abstract

INTRODUCTION The aim of this study was to find out if (90)Y could form a stabile complex with meso-2,3-dimercaptosuccinic acid (DMSA) and if (90)Y-DMSA may have potential for tumor therapy in the palliative treatment of bone metastases. METHODS The preparing of (90)Y-DMSA was carried out by varying experimental parameters, such as ligand concentration, pH… (More)
DOI: 10.1089/cbr.2008.0499

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