Preparation and in vitro evaluation of an ultrasound-triggered drug delivery system: 10-hydroxycamptothecin loaded PLA microbubbles.

@article{Hou2012PreparationAI,
  title={Preparation and in vitro evaluation of an ultrasound-triggered drug delivery system: 10-hydroxycamptothecin loaded PLA microbubbles.},
  author={Zhenqing Hou and Le Li and Chuanming Zhan and Peijuan Zhu and D. Chang and Qiwei Jiang and Shefang Ye and Xiangrui Yang and Yang Li and Liya Xie and Qiqing Zhang},
  journal={Ultrasonics},
  year={2012},
  volume={52 7},
  pages={836-41}
}
10-Hydroxycamptothecin (HCPT) loaded PLA microbubbles, used as an ultrasound-triggered drug delivery system, were fabricated by a double emulsion-solvent evaporation method. The obtained microbubbles were characterized by scanning electron microscope (SEM), transmission electron microscope (TEM), X-ray diffraction (XRD), differential scanning calorimetry (DSC) and confocal laser scanning microscope (CLSM). In addition, the effect of diagnostic ultrasound exposure on BEL-7402 cells combined with… CONTINUE READING
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