Preparation and evaluation of floating risedronate sodium Gelucire 39/01 matrices.
@article{Chauhan2004PreparationAE, title={Preparation and evaluation of floating risedronate sodium Gelucire 39/01 matrices.}, author={B. Chauhan and S. Shimpi and K. Mahadik and A. Paradkar}, journal={Acta pharmaceutica}, year={2004}, volume={54 3}, pages={ 205-14 } }
Incorporation of bisphosphonates in the lipid reduces gastric irritation. Only gastric retention with sustained release allows the drug to reach the duodenum and jejunum and improves the availability of bisphosphonates. Risedronate sodium and Gelucire 39/01 floating matrices were prepared using melt solidification. The sustained release floating matrices were evaluated for in vitro and in vivo floating ability and in vitro drug release. Ageing of the matrices was studied by differential… CONTINUE READING
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References
SHOWING 1-10 OF 32 REFERENCES
In vivo evaluation of rapid release and sustained release Gelucire capsule formulations
- Chemistry
- 1990
- 68
Effect of drug solubility and different excipients on floating behaviour and release from glyceryl monooleate matrices.
- Chemistry, Medicine
- International journal of pharmaceutics
- 2004
- 98
Effects of various absorption enhancers on transport of clodronate through Caco-2 cells.
- Chemistry, Medicine
- International journal of pharmaceutics
- 2003
- 38
Self-emulsifying drug delivery systems: assessment of the efficiency of emulsification
- Chemistry
- 1985
- 267
Administration routes and delivery systems of bisphosphonates for the treatment of bone resorption.
- Medicine
- Advanced drug delivery reviews
- 2000
- 221
AIR COMPARTMENT MULTIPLE – UNIT SYSTEM FOR PROLONGED GASTRIC RESIDENCE (PART I. FORMULATION STUDY)
- Chemistry
- 1998
- 227
In vitro assessment of oral lipid based formulations.
- Chemistry, Medicine
- Advanced drug delivery reviews
- 2001
- 370