Preparation and evaluation of PLGA microparticles as carrier for the pulmonary delivery of rhIL-2 : I. Effects of some formulation parameters on microparticle characteristics.

@article{Devrim2011PreparationAE,
  title={Preparation and evaluation of PLGA microparticles as carrier for the pulmonary delivery of rhIL-2 : I. Effects of some formulation parameters on microparticle characteristics.},
  author={Burcu Devrim and Asuman Bozkir and Kandemir Canefe},
  journal={Journal of microencapsulation},
  year={2011},
  volume={28 6},
  pages={582-94}
}
In this study, recombinant human interleukin-2 (rhIL-2) containing poly(lactic-co-glycolic acid) (PLGA) microparticles were prepared for pulmonary administration by modified w/o/w double emulsion solvent extraction method and the effects of various formulation parameters on the physicochemical properties of the microparticles were investigated… CONTINUE READING