• Chemistry
  • Published 2007

Preparation and dissolution of Breviscapine sustained release solid dispersions

@inproceedings{Ping2007PreparationAD,
  title={Preparation and dissolution of Breviscapine sustained release solid dispersions},
  author={Wei Ping},
  year={2007}
}
OBJECTIVE To prepare Breviscapine sustained release solid dispersion.METHODS Sustained release solid dispersions have been prepared by the solvent method,using different amount and viscosity of ethylcellulose(EC) as carriers and sparingly water-soluble breviscapine as a model drug. RESULTS Breiscapine release profiles of the drug fitted the Higuchi model.By increasing the amount and viscosity of EC,and inlongation of drug release was primarily associated with an increase in a mount of EC and… CONTINUE READING