Preparation and characterization of solid dispersions of dipyridamole with a carrier "copolyvidonum Plasdone S-630".

@article{Chen2007PreparationAC,
  title={Preparation and characterization of solid dispersions of dipyridamole with a carrier "copolyvidonum Plasdone S-630".},
  author={Shengjun Chen and Jiabi Zhu and Fengqin Ma and Qun Fang and Yinghuan Li},
  journal={Drug development and industrial pharmacy},
  year={2007},
  volume={33 8},
  pages={888-99}
}
Solid dispersions (SDs) of dipyridamole (DIP) with a novel carrier copolyvidonum Plasdone S-630 (CoPVP) were developed by solvent evaporation method. The solid state of SDs of DIP with CoPVP (SDs CoPVP) was characterized by fourier transform infrared spectroscopy (FT-IR), differential scanning calorimetry (DSC), X-ray diffraction (XRD) and polarizing microscopy, compared with that of SDs of DIP with polyvinylpyrrolidone Plasdone K-29/32 (SDs PVP). FT-IR analysis demonstrated the presence of… CONTINUE READING

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