Preparation and characterization of quercetin and rutin cyclodextrin inclusion complexes.

@article{Sri2007PreparationAC,
  title={Preparation and characterization of quercetin and rutin cyclodextrin inclusion complexes.},
  author={K. Vijaya Sri and A Kondaiah and J. Vijaya Ratna and Akula Annapurna},
  journal={Drug development and industrial pharmacy},
  year={2007},
  volume={33 3},
  pages={245-53}
}
The objective of the present study is to prepare and characterize cyclodextrin inclusion complexes of quercetin and rutin to improve their aqueous solubility and dissolution properties. Inclusion complexes of quercetin and rutin with beta-cyclodextrin (beta-CD) and hydroxyl propyl-beta-cyclodextrin (HP-beta-CD) were prepared by kneading and coevaporation methods. Characterization of inclusion complexes was done by phase solubility analysis and was supported by X-ray powder diffractometry (XRD… CONTINUE READING

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