The hydrogels are 3D hydrophilic networks of homopolymeric or heteropolymeric chains which were first synthesized by Wichterle and Lim in 1954. The cross-linked hydrogels have the capability of absorbing huge amount of water without itself dissolving in it. The capacity to store water, softness and smartness make hydrogel a unique and ideal material. Hydrogels were prepared using gelatin and carrageenan in this work. The model drug used was ciprofloxacin. And the various characterizations like bright field microscopy, swelling profile, drug release studies and antimicrobial studies were done.