Preparation and characterization of electrospun PLGA/gelatin nanofibers as a drug delivery system by emulsion electrospinning.

@article{Hu2013PreparationAC,
  title={Preparation and characterization of electrospun PLGA/gelatin nanofibers as a drug delivery system by emulsion electrospinning.},
  author={Jun Hu and Junchao Wei and Wanyun Liu and Yiwang Chen},
  journal={Journal of biomaterials science. Polymer edition},
  year={2013},
  volume={24 8},
  pages={972-85}
}
Novel biocompatible poly(lactide-co-glycolide) (PLGA) nanofiber mats with favorable biocompatibility and good mechanical strength were prepared, which could serve as an innovative type of tissue engineering scaffold or an ideal controllable drug delivery system. Both hydrophobic and hydrophilic drugs, Cefradine and 5-fluorouracil were successfully loaded into PLGA nanofiber mats by emulsion electrospinning. The natural bioactive protein gelatin (GE) was incorporated into the nanofiber mats to… CONTINUE READING